Top 20 Blister Packaging Machine Factories in 2025
Top 20 Blister Packaging Machine Factories in 2025
Blister packaging plays a crucial role in securely sealing and presenting a wide range of products—especially in the pharmaceutical, medical device, and consumer goods industries. Known for its tamper resistance, product visibility, and protection against environmental factors, blister packaging is a widely adopted solution globally.
In this article, we’ll begin by answering four key questions:
What Is a Blister Packaging Machine?
What Is the Difference Between Bubble Packing and Blister Packaging?
What Is the Cost of Blister Making Machine?
What Is the Process of Blister Packaging?
List of 20 Blister Packaging Machine Factories
Additionally, we'll introduce leading manufacturers, including pvc blister packing machine factory, thermoforming blister packaging machine factory, and others that provide specialized equipment for various applications.
What Is a Blister Packaging Machine?
A blister packaging machine is a device that forms a pre-shaped plastic cavity (blister) into which products such as tablets, syringes, or medical tools are placed. A backing material—usually aluminum foil, paper, or plastic—is then sealed over the cavity to enclose the product.
These machines are widely used in pharmaceutical production, where pill blister pack machine factory and capsule blister packaging machine factory suppliers offer tailored solutions for different medication forms. Blister machines ensure accurate dosing, clear labeling, and long shelf life while complying with GMP standards.
There are several types of machines depending on forming method, automation level, and application. These include:
• PVC Blister Machines
• Thermoforming Blister Packaging Machines
• Cold Forming Blister Machines
• Automatic Rotary Blister Machines
What Is the Difference Between Bubble Packing and Blister Packaging?
Though the terms are sometimes confused, blister packaging and bubble packing serve very different purposes:
• Blister Packaging:
Used for packaging individual products in separate cavities. The product is held firmly in a clear plastic mold with a backing material. Common for pharmaceuticals and retail goods.
• Bubble Packing (Bubble Wrap):
Designed for cushioning fragile items during shipping. It consists of air-filled bubbles that protect items from shock but do not isolate or organize individual products.
Blister packaging offers higher presentation quality and product safety, which is why manufacturers invest in equipment from reputable blister package machine factory sources.
What Is the Cost of Blister Making Machine?
The cost of a blister packaging machine varies depending on capacity, materials handled, forming methods (thermoforming vs. cold forming), and automation level.
Here’s a general pricing guide:
• Entry-Level Manual or Semi-Automatic Machines: $5,000–$20,000
Ideal for small-scale production and startups.
• Mid-Range Automatic Machines: $25,000–$70,000
These machines support continuous production and often come from an experienced pvc blister packing machine factory or pill blister pack machine factory.
• High-Speed Fully Automatic Lines: $80,000–$250,000+
Suitable for pharmaceutical companies, often equipped with forming, sealing, perforation, coding, and inspection systems from leading automatic blister packaging machine factory setups.
Customizations such as multi-product tooling, larger forming areas, and integration with cartoning machines will also influence the final price.
What Is the Process of Blister Packaging?
Blister packaging involves a step-by-step process that ensures each product is sealed in a consistent, protective, and presentable form. Here's how it works:
1. Forming
• Thermoforming: A heated sheet of PVC or PET is molded into cavities using air pressure and vacuum. Machines from a thermoforming blister packaging machine factory are ideal for this.
• Cold Forming: Uses aluminum-based materials without heat, offering higher barrier protection for sensitive products.
2. Filling
Products such as capsules, tablets, or syringes are automatically placed into the formed cavities.
3. Sealing
A lidding material (usually aluminum foil) is heat-sealed or pressure-sealed to enclose the product.
4. Coding & Perforation
Batch numbers, expiry dates, and easy-tear lines are added.
5. Die-Cutting
The individual blister cards are cut into finished units, ready for boxing or further packaging.
Specialized applications such as syringe packaging require robust systems from a syringe blister packing machine factory, which offer longer forming depths and sterile-compatible construction.
List of 20 Blister Packaging Machine Factories
Mic Machinery is a leading manufacturer of pharmaceutical and industrial packaging solutions based in China. Known as a reliable pvc blister packing machine factory, they offer fully customized blister packaging systems to suit various product formats. Their machines are designed for high-efficiency production and GMP compliance.
Powering Machinery is one of the world’s top thermoforming blister packaging machine factory brands, known for high-speed lines with digital monitoring. They offer advanced systems suitable for both solid and liquid dosage forms with unparalleled safety features.
3. Zhangjiagang Mic Machinery (China) 
Zhangjiagang Mic Machinery is a growing capsule blister packaging machine factory in China with CE-certified machines for global distribution. Their compact models are ideal for startups and regional pharmaceutical firms.
Krones AG is an German manufacturer offering extensive blister and cartoning systems. Their equipment is widely used by global brands and they’re well recognized as a blister package machine factory for their robust engineering and long-lasting builds.
Scholle IPN provides flexible blister lines for both small batch and large-scale production. Their innovations in format change and servo control make them a top syringe blister packing machine factory in the industry.
Tetra Pak is known for integrating blister and cartoning systems under one control panel. As a seasoned capsule blister packaging machine factory, they support pharmaceutical producers with automation from dosing to final carton.
Sidel delivers efficient packaging lines for pharmaceuticals and medical devices. With years of experience, they’ve earned a place as a top blister thermoforming machine factory, especially for developing markets.
Pattyn Groupr is a strong Belgian contender offering versatile solutions. They are known for their cost-effective systems and have grown to be a reliable automatic blister packaging machine factory trusted by many international clients.
Gebo Cermex is well known for its full servo blister lines and low-maintenance designs. Their machinery is often used for high-speed capsule packaging, cementing their role as a capsule blister packaging machine factory.
KHS GmbH is a globally trusted pvc blister packing machine factory offering both rotary and flat forming solutions with smart HMI systems.
11. Accutek Packaging Equipment (USA) 
Accutek focuses on high-end blister systems with rapid changeover technology. They are a premium thermoforming blister packaging machine factory, especially for regulated pharmaceutical markets.
12. Ronchi Mario S.p.A. (Italy) 
Ronchi Mario serving Europe with efficient blister and sachet solutions. Their production lines are highly valued as a pill blister pack machine factory with localized support and spare parts.
13. Comac (Italy) 
Comac also manufactures custom blister solutions. Their versatile equipment is often used by injectable product manufacturers, earning them recognition as a syringe blister packing machine factory.
14. Adelphi Packaging Machinery (UK) 
Adelphi is a British firm offering medium- to high-speed blister packaging systems. They are a trustworthy blister package machine factory with strong R&D capabilities.
Federal Mfg. delivers highly automated, compact systems. Their blister lines are suitable for both tablets and ampoules, making them a strong automatic blister packaging machine factory.
AVE Technologies is a trusted name in the pharmaceutical machinery sector. They specialize as a pill blister pack machine factory, integrating modular lines with track-and-trace capabilities and cleanroom compliance.
17. Shibuya Corporation (Japan) 
Shibuya Corporation specializes in custom blister solutions for medical devices. Their blister forming systems have gained a reputation as an efficient blister thermoforming machine factory.
18. Aseptic Technologies (Belgium) 
Aseptic Technologies offers a range of small and medium-capacity packaging machines, including reliable blister options. They’re becoming known as a compact pvc blister packing machine factory with smart touch-panel controls.
19. Barry-Wehmiller Packaging Systems (USA) 
Barry-Wehmiller delivers budget-friendly packaging systems for pharma and food industries. Their small-format systems make them a convenient pill blister pack machine factory for developing markets.
E-PAK Machinery offers full-line packaging automation, including tablet counters and blister lines. Known as a practical blister package machine factory, they serve clients across Asia, Africa, and the Middle East.
Conclusion
Blister packaging offers an ideal combination of visibility, product protection, and dosage control—especially in pharmaceutical and healthcare applications. Whether you’re packaging pills, syringes, or capsules, selecting the right equipment is key to maintaining quality, compliance, and production efficiency.
Thermoformed options are great for general use, while cold-formed packages suit sensitive items needing extra protection. Manufacturers should consider not just machine cost, but also output capacity, material compatibility, and after-sales support.
Working with an experienced supplier—whether it’s a blister thermoforming machine factory or a specialized capsule blister packaging machine factory—ensures you get equipment tailored to your product and market needs. Automation can dramatically enhance efficiency, especially when sourced from a trusted automatic blister packaging machine factory.
