Top 20 Blister Packaging Equipment Factories in 2025
Top 20 Blister Packaging Equipment Factories in 2025
Blister packaging remains a critical solution in the pharmaceutical and healthcare sectors due to its precision, hygiene, and protective features. It offers unit-dose packaging, protects medication from contamination and moisture, and enhances tamper evidence. Before choosing the right system, it's important to understand some key aspects, such as:
What Materials Are Used in Blister Packaging?
What Is the Mechanism of a Blister Packing Machine?
What Are the Problems With Blister Packaging?
How Do You Test for Blister Packaging?
Types of Blister Packaging Equipment in the Pharmaceutical Industry
Applications in the Pharmaceutical Industry
List of 20 Blister Packaging Equipment Factories
This article answers these essential questions and introduces how leading blister packaging equipment factory solutions power today’s pharma production.
What Materials Are Used in Blister Packaging?
Blister packaging typically consists of two main components: the forming film and the lidding material.
• Forming Film (Blister): Made from thermoformable plastic like PVC, PVDC, or aluminum-based laminates. These materials provide the pocket that houses the product.
• Lidding Material: Usually aluminum foil, offering excellent barrier protection and sealability. In some applications, paper or plastic film is also used.
Top-tier automatic blister packing machine factory manufacturers ensure that machines handle a variety of material combinations without compromising packaging integrity.
What Is the Mechanism of a Blister Packing Machine?
Blister packaging machines operate on thermoforming or cold forming principles, with multiple synchronized processes:
1. Forming: Heating (for thermoform) or pressing (for cold form) the base material into a cavity or mold.
2. Filling: Tablets, capsules, or other items are accurately placed into the formed cavities.
3. Sealing: The lidding foil is applied and sealed with pressure and heat.
4. Cutting: Individual blister cards are die-cut into the desired size and shape.
Modern systems from a trusted automatic blister machine factory are fully automated and integrated with servo motors, PLCs, and touchscreens for seamless control and efficiency.
What Are the Problems With Blister Packaging?
Despite its advantages, blister packaging may encounter several challenges:
• Seal Integrity Issues: Improper heat or pressure can cause weak or incomplete seals.
• Material Incompatibility: Some drugs react with PVC, requiring special laminates.
• Misfeeds or Misalignment: Mechanical issues may cause incorrect filling or positioning.
• Environmental Impact: Non-recyclable multilayer materials can contribute to waste.
By sourcing from a reliable blister pack machine factory or blister pack equipment factory, many of these challenges can be reduced or eliminated with advanced technology and quality assurance systems.
How Do You Test for Blister Packaging?
Blister packaging quality testing ensures that the final product is both safe and tamper-evident. Common tests include:
• Visual Inspection: Checks for misaligned seals, deformations, or contamination.
• Vacuum Leak Test: Detects seal integrity and potential air or moisture entry.
• Burst and Peel Strength Tests: Measures the force needed to open a sealed blister.
• Accelerated Aging Tests: Assesses durability under stress conditions like heat and humidity.
Professional pharma blister packaging machine factory systems often include integrated vision inspection systems and data recording capabilities for 100% quality control.
Types of Blister Packaging Equipment in the Pharmaceutical Industry
Pharmaceutical blister machines come in many configurations, each suited to different production scales and product types. Leading blister forming machine factory and pharmaceutical blister packaging machine factory suppliers provide:
• Rotary Blister Machines: Ideal for medium to large batch sizes with continuous operation.
• Flat Plate Blister Machines: Known for high-precision sealing, especially in small runs.
• Cold Forming Machines: For products highly sensitive to light and moisture.
• Capsule-Focused Equipment: Designed specifically for capsules and hard gel formats.
Each system is developed with user safety, speed, and GMP compliance in mind.
Applications in the Pharmaceutical Industry
Blister packaging plays a vital role in medicine packaging due to its convenience and effectiveness. In fact, nearly every blistering machine in pharmaceutical industry factory prioritizes:
• Tamper Resistance: Prevents unauthorized access to medication.
• Product Protection: Keeps drugs safe from moisture, light, and contamination.
• Dosing Accuracy: Enables unit-dose formats for patient safety and compliance.
Trusted blister packaging machine pharmaceutical industry factory partners offer full-service customization, allowing clients to adjust layout, format, and packaging output to suit different pharmaceutical needs.
List of 20 Blister Packaging Equipment Factories
Mic Machinery stands out as a reliable automatic blister packing machine factory, providing efficient solutions tailored for the pharmaceutical, cosmetic, and food industries. As a leading blister packaging equipment factory, Mic focuses on integrating high automation and precision, especially for capsule, tablet, and softgel applications.
Powering Machinery is one of the most renowned names in the pharmaceutical sector, known as a top pharmaceutical blister packaging machine factory. Their cutting-edge lines serve global pharma companies with fully automated, high-output packaging solutions.
3. Zhangjiagang Mic Machinery (China) 
Zhangjiagang Mic Machinery is a top-tier blister pack machine factory offering advanced equipment for tablets and capsules. Their solutions are especially well-suited for the pharma blister packaging machine factory market, incorporating high-speed operations with stringent hygiene standards.
Krones AG is a leading blister packaging machine pharmaceutical industry factory that delivers modular systems for high-volume and flexible production. Their equipment supports diverse formats and materials, serving global pharmaceutical manufacturers.
Scholle IPN is widely recognized as an expert automatic blister machine factory with decades of experience in pharma packaging. Their machines combine compact design with advanced servo-driven technology for efficient blistering.
Tetra Pak is a prominent blister forming machine factory and a reliable partner for mid- to high-speed pharmaceutical blister production. Known for their flexible designs, they accommodate a wide range of blister pack sizes and materials.
Sidel is a global blistering machine in pharmaceutical industry factory offering isolator-compatible and high-containment solutions. Their equipment ensures reliability and compliance with international pharmaceutical standards.
Pattyn Group is a specialized capsule blister packing machine factory with a strong presence in the Asian and European markets. Their machines are valued for cost-efficiency and precision in tablet and capsule packaging.
Gebo Cermex provides innovative, sustainable packaging solutions and is recognized as a dependable blister packaging equipment factory. Their machines feature robotic integration and real-time monitoring systems.
KHS GmbH develops sterile blister systems, positioning itself as a trusted blister pack equipment factory. Their machines are widely used in biotech and specialty pharma production.
11. Accutek Packaging Equipment (USA) 
Accutek is a specialized blister forming machine factory offering both production and blister leak testing equipment. Their compact, benchtop blister machines serve clinical trials and R&D operations.
12. Ronchi Mario S.p.A. (Italy) 
Ronchi Mario is a rapidly growing automatic blister packing machine factory known for durable and user-friendly systems. Their solutions are well-suited for generics manufacturers and medium-scale production.
13. Comac (Italy) 
Comac is a global pharmaceutical blister packaging machine factory delivering complete blister-to-carton solutions. They have a strong footprint across Asia, Africa, and Latin America.
14. Adelphi Packaging Machinery (UK) 
Adelphi is a UK-based blister packaging machine pharmaceutical industry factory, particularly strong in aseptic packaging and solid dosage forms. Their machines offer full compliance with GMP and EU standards.
Federal Mfg. is a high-end pharma blister packaging machine factory offering highly flexible systems for capsules, vials, and syringes. Their blister lines are often combined with track-and-trace and vision systems.
AVE Technologies is a cost-competitive capsule blister packing machine factory, especially for startups and medium-sized enterprises. Their automation levels are high, and their machines support a variety of blister formats.
17. Shibuya Corporation (Japan) 
Shibuya Corporation builds secondary packaging lines and is aligned with many blister pack equipment factory systems. Their solutions streamline the post-blister packaging phase, enhancing production efficiency.
18. Aseptic Technologies (Belgium) 
Aseptic Technologies is a versatile Chinese automatic blister machine factory known for pharmaceutical and nutraceutical packaging systems. They focus on compact, integrated equipment that supports both high-speed and lab-scale operations.
19. Barry-Wehmiller Packaging Systems (USA) 
Barry-Wehmiller specializes in cold seal and pressure blister technology. As a unique blister packaging equipment factory, their focus is on sustainable and environmentally friendly blister solutions.
E-PAK Machinery supports domestic clients with localized service for high-end blister packaging machine pharmaceutical industry factory solutions. Their support structure and spare parts availability make them a strong option for U.S. firms.
This selection of global leaders in blister packaging equipment factory solutions highlights the diverse offerings and specialties across the market. Whether you’re looking for compact blister solutions or fully integrated pharma lines, these factories have the capabilities to meet stringent industry needs.
Conclusion
Blister packaging equipment is a cornerstone of modern pharmaceutical manufacturing. Understanding materials, machine mechanisms, potential challenges, and testing methods is essential for selecting the right solution. Whether you're seeking high-speed automation or small-batch flexibility, top automatic blister packing machine factory, capsule blister packing machine factory, and pharma blister packaging machine factory providers deliver solutions tailored for efficiency, compliance, and product integrity.
